Title: “Myofibroblast Mechanobiology and Implications for Implant Fibrosis”
Dr. Boris Hinz
Keenan Research Chair in Fibrosis Research, St. Michael’s Hospital
Professor, University of Toronto
Date: Friday, March 4, 2022 | 1pm – 2pm EST
Join Zoom Meeting: https://ryerson.zoom.us/j/99770279843?pwd=SE5PbjVqMWNGdXRIVDRSWHBici9WZz09
Host: Dr. Michael Kolios
LECTURE TAKEAWAYS:
- Learn about mechanical activation of fibroblasts in health and disease
- Understand fibroblast activation and how it contributes to failure of body implants
- Discuss strategies to prevent fibroblast-driven implant fibrosis
BIOGRAPHY
Dr. Boris Hinz is Keenan Research Chair in Fibrosis Research at St. Michael’s Hospital and University of Toronto Distinguished Professor in Tissue Repair and Regeneration. He is appointed within the Faculties of Dentistry, Medicine, and Biomedical Engineering. Dr. Hinz is secretary and inaugural board member of the Canadian Connective Tissue Society, and board member of the International Dupuytren Society and the Canadian Dupuytren Society. He has been president and board member of the European Tissue Repair Society and was board member of the Wound Healing Society. He is Editor-in-Chief (basic science) of the journal, “Wound Repair and Regeneration”; Section Editor of the “Journal of Investigative Dermatology”; Associate Editor of “Biochemistry and Cell Biology”; and editorial board member of “Matrix Biology” and “Experimental Dermatology”.
Dr. Hinz studies the role of contractile myofibroblasts in physiological tissue repair and in causing pathological tissue fibrosis. The findings of his lab are published in peer-reviewed journals, including “Cell”, “Nature Materials”, “Nature Biomedical Engineering”, “Cell Stem Cell” and many more. His research led to the creation of two startup companies specialized in anti-fibrotic coatings for silicone implants and novel “soft” cell culture devices. Dr. Hinz’s research is currently funded by a multi-project Foundation Grant from the Canadian Institutes of Health Research (CIHR), CIHR operating funds, the Canada Foundation for Innovation (CFI), the Ontario Research Foundation (ORF) and MITACS (Mathematics of Information Technology and Complex Systems).
No sign-up required. For more information contact the iBEST Coordinator (ibest@ryerson.ca).
